Fecha/hora: 03/06/2024 08:43:52

Biblioteca(s): 	INIA La Estanzuela.	
Tipo de la producción científica: 	Artículos en Revistas Indexadas Internacionales	
Circulación/Nivel: 	Internacional - --	
Fecha corriente: 	27/11/2020	
Fecha de la última actualización: 	27/11/2020	
Autoria: 	CASTELLS, M.; CAFFARENA, D.; CASAUX, M.L.; SCHILD, C.; CASTELLS, F.; CASTELLS, D.; VICTORIA , M.; RIET-CORREA, F.; GIANNITTI, F.; PARREÑO, V.; COLINA, R.	
Afiliación: 	MATÍAS CASTELLS BAUER, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay./Matías Castells Laboratorio de Virología Molecular, CENUR Litoral Norte, Centro Universitario de Salto, Universidad de la República, Rivera 1350, 50000 Salto, Uruguay.; RUBEN DARÍO CAFFARENA LEDESMA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay./Facultad de Veterinaria, Universidad de la República, Alberto Lasplaces 1620, Montevideo, Uruguay.; MARÍA LAURA CASAUX, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; CARLOS SCHILD, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; FELIPE CASTELLS, Felipe Castells Doctor en Veterinaria en ejercicio libre, asociado al Laboratorio de Virología Molecular, CENUR Litoral Norte, Centro Universitario de Salto, Universidad de la República, Uruguay.; DANIEL CASTELLS, Centro de Investigación y Experimentación Dr. Alejandro Gallinal, Secretariado Uruguayo de la Lana, Ruta 7 km 140, Cerro Colorado, Florida, Uruguay.; MATÍAS VICTORIA, Laboratorio de Virología Molecular, CENUR Litoral Norte, Centro Universitario de Salto, Universidad de la República, Rivera 1350, 50000 Salto, Uruguay.; FRANKLIN RIET-CORREA AMARAL, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; FEDERICO GIANNITTI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; VIVIANA PARREÑO, Sección de Virus Gastroentéricos, Instituto de Virología, CICV y A, INTA Castelar, Buenos Aires, Argentina.; RODNEY COLINA, Laboratorio de Virología Molecular, CENUR Litoral Norte, Centro Universitario de Salto, Universidad de la República, Rivera 1350, 50000 Salto, Uruguay.	
Título: 	Detection, risk factors and molecular diversity of norovirus GIII in cattle in Uruguay.	
Año de publicación: 	2020	
Fuente/Imprenta: 	Infection, Genetics and Evolution, December 2020, Volume 86, Article number 104613. Doi: https://doi.org/10.1016/j.meegid.2020.104613	
DOI: 	10.1016/j.meegid.2020.104613	
Idioma: 	Inglés	
Notas: 	Article history: Received 1 August 2020 / Revised 27 October 2020 / Accepted 28 October 2020 / Available online 4 November 2020./ Corresponding authors at.: Laboratorio de Virología Molecular, CENUR Litoral Norte, Centro Universitario de Salto, Universidad de la República, Rivera, 1350,50000 Salto, Uruguay.	
Contenido: 	Abstracts. Uruguay is a leading exporter of bovine meat and dairy products, and cattle production is one of the principal economic backbones in this country. A main clinical problem faced by livestock farmers is neonatal calf diarrhea (NCD); however, causes of NCD have not been extensively studied in Uruguay. Bovine norovirus (BoNoV) has been proposed as one of the possible etiologies of NCD as experimentally infected calves developed diarrhea and enteropathy, although limited information is available from field surveys. The aims of this study were to
determine the frequency of infection, to investigate possible risk factors, and to determine the molecular diversity of BoNoV in Uruguay. A total of 761 samples of feces or intestinal contents from dairy and beef calves were analyzed through RT-qPCR. The overall frequency of detection of BoNoV was 66.1% with higher frequency in dairy (70.5%) than beef (15.9%) calves (p < 0.01). BoNoV was detected similarly in diarrheic (78.8%) and non-diarrheic (76.2%) dairy calves (p = 0.50). Calves ?2 weeks of age (84%) were infected more often than older
(62.7%) calves (p < 0.01). Phylogenetic analysis confirmed the presence of GIII.1 and GIII.2 genotypes. In addition, we reported the circulation of recombinant strains and the detection of a strain with the recently described novel VP1 genotype. This study represents the first report describing the circulation, the associated risk factors, and the molecular diversity of BoNoV in Uruguay.	
Palabras-Clave: 	BOVINE NOROVIRUS; CATTLE; DIARRHEA; GENOTYPES; PLATAFORMA DE SALUD ANIMAL.	
Thesagro: 	GANADERIA; URUGUAY.	
Categoría del tema: 	L73 Enfermedades de los animales	
Registro original: 	INIA La Estanzuela (LE)	
Ejemplares: 	LE - (103245-1) - PXI - AP - DD - PP/Inf Gen. Evo./2020 -  -  - DIS